The DCRI Electronic Electrocardiographic (eECG) Core Laboratory is the largest and most experienced academic eECG core laboratory in the world. More than 10 million high-fidelity digital 12-lead ECGs have been analyzed and archived in our lab over the past 20 years. It also is the only such core laboratory in the world to support global point-of-care digital acquisition of ECGs from clinical sites using their own equipment.

The eECG Core Laboratory has experience with more than 500 sites around the world. Site-friendly data collection spans the full range of patient-care environments, including ambulatory units, pre-hospital settings, emergency departments, chest pain units, cardiac catheterization labs, coronary and intensive care units, operating rooms, general wards, and dialysis, endoscopy, and bronchoscopy wards. Clinical trials include cardiology trials, where eECG data such as measures of ischemia or infarction are used to assess therapeutic efficacy, and noncardiology trials, where eECG data such as changes in the QT interval are used to assess therapeutic safety.

The DCRI eECG core lab is staffed by a team of dedicated medical research professionals, including an operations manager, project leaders, site managers, nurse coordinators, technicians, data managers, and administrative support staff.

Contacts
General contact: Tracey Harrill, RN (Global Business Development Representative)>
Director: Mitchell W. Krucoff, MD, FACC
Director Safety/Arrhythmia Monitoring: Christopher H. Cabell, MD
Vice President / General Manager: Dianne Cheesborough, RN
Senior Statistical Advisor: Cynthia L. Green, PhD

• Continuous 12-lead ECG
• Static ECG
• Electronic QT/QTc safety analysis, including central tendency, categorical and morphological waveform analysis
• Holter monitoring
• 12-lead exercise treadmill testing
• Specialty applications: vector cardiography, derived ECG monitoring, precordial mapping

Why an Academic eECG Lab?
Regulatory requirements for safety and efficacy data based in ECG measurements are rapidly evolving toward high-fidelity digital formats. Such formats provide both more precise measurements and more complete records. Academic core labs such as the DCRI’s eECG lab also participate in and help define technological innovation in the context of clinical and strategic insight and clinical trials expertise. Application of cutting-edge technology, site-sensitive configurations, and faculty insights into elements of data quality and interpretation support data excellence that serves clinical trial and client goals. Further, the overall value of eECG information is far superior to that of commercial ECG core labs, with comparable costs. Finally, unique, additional efficiencies are realized in trials coordinated by the DCRI as a whole.